Mordechai Moreh was born in Baghdad, Iraq, in 1937 to a well-to-do Jewish family. His grandmother ran an embroidery workshop. When he was 14, he immigrated to Israel with his cousin and was sent to the "Sha'ar Aliyah" immigrant camp and various transit camps. In 1952, he and his mother immigrated with the Talpiot transit camp in Jerusalem. In 1955 he began studying at Bezalel Academy, later stuying in it's newly opened art department. In 1960 he exhibited his first solo exhibition at the Rina Gallery in Jerusalem. In the early sixties he went to study in Italy and then in France. Since the 1970s he has been living and working in France and Israel.
Moreh's work is influenced by mysticism and Surrealist art. Among the motifs used in his work are images of many animals, especially cats, symbolizing the mystery of the night, images of carnival and more.