Jacob Eisenscher (1896-1980) was born in Czernowitz, Bukovina, then part of the Austro-Hungarian Empire. In his youth, he studied at the School of Art in Vienna. At the end of the first world war he returned to Czernowitz and made a living from photography. During this period he created an oil painting alongside woodcuts. In the early 1930s he emigrated to Paris, France. There, he was exposed to cubist art. In 1935 he immigrated to Israel and in 1952 he began teaching art at the Bezalel Academy of Arts and Design.
Eisenscher's early works bear archaic characteristics. He used to create portraits and depictions of characters and styles in an expressive style influenced by German Expressionism. In the later years he created many oil paintings, depicting landscapes and houses in a style influenced by Cubism. Among his well known works are the group of paintings "Sha'ar" (1969) and the "Night of November 29th" from the Knesset collection.
A collection of his estate, including letters and photographs, is in the Collection of the Information Center for Israeli Art at the Israel Museum, Jerusalem.